- Avidemux is now time-based instead of frame-based to provide better accuracy when dealing with variable frame rate sources
- Demuxers, muxers, video decoders, FFmpeg encoders and scripting engines are now plugins
- Updated FFmpeg libraries (version 0.11.1)
- Improved threading when decoding and encoding video
- Job queue functionality has been moved to a separate application
- Removed VOB to VobSub, VobSub to srt, and TS to srt subtitle tools
- Removed language translations
- The same video renderer is now used when editing and playing video for consistency
- Accelerated video decoding on Linux when using NVIDIA GeForce 8 series or later GPU
- Support for Sorenson Vector Quantizer 1 video decoding
- Support for E-AC3 audio decoding
- New AAC audio encoder (avcodec)
- Increased the maximum number of supported input/output audio tracks from 2 to 4 for applicable video containers
- Audio filters can now be applied to all audio tracks (not just the primary track)
- AAC LATM/LOAS audio support for the MPEG-TS demuxer
- MPEG-4 AVC and AAC support for the Flash Video demuxer
- Improved OpenDML support for the AVI muxer
- New MP4 muxer (MP4v2)
- Removed the Ogg muxer
- New Python scripting engine (TinyPy)
- New ECMAScript scripting engine (QtScript) including debugger and reference guide
- New Transform video filters: Resize (swscale), Greyscale, Add Logo, Horizontal Flip
- New Colour video filter: Remove Plane
- New Miscellaneous video filter: PrintInfo
- New OpenGL video filters for Apple and Linux operating systems
- Removed Transform video filters: Reverse, Resize, Fade, MPlayer Resize
- Removed Interlacing video filters: Deinterlace, Drop, Keep Even Fields, Keep Odd Fields, mcDeinterlace, PAL Field Shift, Pulldown, PAL Smart, Smart Swap Fields, Swap Fields, TDeint
- Removed Colour video filters: Blend Removal, Colour Curve Editor, Luma Delta, Luma Only, Chroma U, Chroma V
- Removed Noise video filters: Cnr2, Denoise, Forced Postprocessing, Median (5x5), Light Denoiser, TIsophote, Temporal Cleaner
- Removed Sharpness video filter: Soften
- Removed Subtitle video filters: VobSub, DVB Sub, ASS, Subtitler
- Removed Miscellaneous video filters: Add Framenumber, Mosaic, Whirl